Following oral administration of radiolabeled zafirlukast to volunteers, urinary excretion accounts for roughly 10% from the dose and the rest is excreted in feces. Zafirlukast will not be detected in urine.

Never share zafirlukast with Others, even when they've a similar affliction as you. It may well harm them.

Severe Allergic Reactions. Zafirlukast might bring about allergic reactions, that may be serious. Cease getting zafirlukast and have support right away When you have any of the next indicators of a serious allergic reaction.

To protect youthful small children from poisoning, normally lock protection caps and instantly location the medication in a safe location – one which is up and away and out of their sight and arrive at.

Renal impairment: Dosage adjustment for sufferers with renal ailment will not be vital with zafirlukast.

Unintended effects that typically do not need medical interest (report back to your care crew whenever they continue on or are bothersome):

This medicine can be used for other applications; request your well being care company or pharmacist For those who have thoughts.

Some Unwanted side effects can be major. For those who practical experience any of the following signs or those mentioned in the Exclusive PRECAUTIONS section, connect with your health practitioner quickly.

Hepatic impairment: Zafirlukast use is not advisable for patients with hepatic impairment on account of compromised hepatic clearance, causing a fifty% to sixty% boost in the utmost plasma concentration.

Pretreatment With all the drug also attenuated the early- and late-phase reactions caused by inhaling antigens which include cat dander, ragweed, grass, and other allergens in persons with asthma. Zafirlukast also mitigated the rise in bronchial hyperresponsiveness to inhaled histamine that followed the inhalation of allergens.

Working with this drugs with any of the next medicines is frequently not proposed, but may be needed in some cases. If each medicines are prescribed with each other, your medical professional may possibly change the dose or how frequently you employ one particular or equally from the medicines.

Cease working with this drugs and Look at along with your medical doctor without delay for those who or your son γ-Tocopherol or daughter have agony or tenderness in the higher belly; pale stools; darkish urine; loss of appetite; nausea; unusual tiredness or weak spot; or yellow eyes or pores and skin. These may very well be indications of a significant liver challenge.

Zafirlukast is actually a medication employed often and isn't for use when a quick response to breathing difficulties is required. Zafirlukast will never prevent a unexpected bronchial asthma attack. Constantly have your rescue inhaler with you for asthma assaults.

While in the pivotal bioequivalence study, the suggest terminal 50 %-lifetime of zafirlukast is roughly 10 hrs in both equally normal adult subjects and individuals with asthma. In other scientific tests, the mean plasma fifty percent-life of zafirlukast ranged from about 8 to 16 hrs in each typical subjects and sufferers with asthma.